Information Resources & Technology


  • Overview

Learning Objectives

  • Classify epidemiology of sepsis syndrome and differentiate between the different forms of sepsis syndromes (simple, severe and septic shock).
  • Integrate best evidence practices, clinical expertise and diagnostic test results for early identification and optimal management of septic states using evidence-based guidelines and clinical decision support tools (eg. ordersets, best practice alerts etc.)
  • Demonstrate specific best practice strategies such as fluid resuscitation, early identification with laboratory markers and screening and transfer of patient to higher care with sepsis.
  • Describe priority actions for establishing and implementing early goal directed therapies for the septic patients along the continuum of care.
  • Develop and apply communication skills related to identification and management of sepsis when working among healthcare teams. (eg. Calling for help early)


Presented by:
Stanford Hospital and Clinics Department of Quality, Patient Safety and Effectiveness

  • Original Release Date:
    December 12, 2011


The following planners, content reviewers, and authors have indicated that they have no relationships with industry to disclose relative to the content of this activity:

Lisa Shieh, MD, PhD
Course Director/Content Reviewer

Clinical Associate Professor of Medicine
Medical Director of Quality, DOM
Stanford University School of Medicine

Eileen P. Pummer, MSN, RN, CPHQ
Course Co-Director/Content Reviewer

Quality Manager
Stanford Hospital & Clinics

William Daines, MD

Clinical Instructor of Medicine
Stanford University School of Medicine

Paul M. Maggio, MD

Assistant Professor of Surgery
Co-Director of Critical Care Medicine
Stanford University Medical Center

Matthew Strehlow, MD

Clinical Assistant Professor of Surgery
Stanford Hospital & Clinics

Irina Tokareva, BSN, MAS, CPHQ

CME Curriculum and Outcomes Manager
Stanford University School of Medicine

Technical Design and Development

Jamie Tsui
Stanford EdTech

Pauline Brutlag
Stanford EdTech

Jonathan Tatum
Stanford EdTech

Brian Tobin
Stanford EdTech

James Laird

Glenn Zephier

System Requirements

Runs best on iPad or Android tablets. On desktop, requires latest Firefox, Google Chrome, or Apple Safari with pop-ups allowed.
Internet Explorer is not supported, and should be closed prior to opening the game.

Contact Information

For further information regarding this game, please send an email to


Sepsis strikes approximately 750,000 people in the US and is responsible for more than 215,000 deaths. Mortality remains high at 25-50% at a cost of $17 billion each year [1]. Septic states have become far too common; with unacceptable high mortality rates and lengthy hospitalizations, it is one of the most costly conditions to treat. This activity provides a practical approach to early sepsis identification and application of evidence-based management (best practice) and evidence-based guidelines. Interactive case scenarios will be used to put these principles into practice.

Intended Audience

Designed for hospital-based medical and surgical, intensive care and emergency department physicians and nurses.

Please note this is an educational tool and the clinical information found in this game is part of an educational material. It should not take the place of practitioner decision-making in clinical circumstances.

1 Angus DC, Linde-Zwirble WT, Lidicker J, Clermont G, Carcillo J, Pinsky MR. Epidemiology of severe sepsis in the United States: Analysis of incidence, outcome, and associated costs of care. Crit Care Med. 2001 Jul;29(7):1303-10.

Change History

Septris is no longer available for CME credit as of March 2014.

Septris updated with a new interface and new features in March 2014, including an action logging feature for debriefing at the end of the game. The new interface does not function well on smartphones, and a tablet or desktop/laptop computer is recommended.

Click HERE to play Septris

Click Here to Submit Feedback

Click here to access the older, smartphone-friendly version of Septris

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